Creer y saber

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SABER Optical Design

SABER, the South Arc Beam Experimental Region, is a proposed new beam line facility designed to replace the Final Focus Test Beam at SLAC. In this paper, we outline the optical design features and beam parameters now envisioned for SABER. A magnetic chicane to compress positron bunches for SABER and a bypass line that could transport electrons or positrons from the two-thirds point of the linac...

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Tamoxifen-Independent Recombination in the RIP-CreER Mouse

BACKGROUND The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen receptor ligand, tamoxifen. The RIP-CreER mouse (Tg (Ins2-cre/Esr1) 1Dam) is among the few available β-ce...

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Fabp4-CreER lineage tracing revealstwo distinctive coronary vascular populations

Over the last two decades, genetic lineage tracing has allowed for the elucidation of the cellular origins and fates during both embryogenesis and in pathological settings in adults. Recent lineage tracing studies using Apln-CreER tool indicated that a large number of post-natal coronary vessels do not form from pre-existing vessels. Instead, they form de novo after birth, which represents a co...

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Genetic targeting of sprouting angiogenesis using Apln-CreER

Under pathophysiological conditions in adults, endothelial cells (ECs) sprout from pre-existing blood vessels to form new ones by a process termed angiogenesis. During embryonic development, Apelin (APLN) is robustly expressed in vascular ECs. In adult mice, however, APLN expression in the vasculature is significantly reduced. Here we show that APLN expression is reactivated in adult ECs after ...

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Saber-sheath trachea in a patient with severe COPD.

To cite: Tunsupon P, Dhillon SS, Harris K, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2016-214648 DESCRIPTION An 86-year-old man was evaluated for chronic cough and right lower lobe (RLL) mass. His medical history was significant for severe chronic obstructive lung disease (COPD). He had smoked one pack of cigarettes daily for 55 years. He had a barre...

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ژورنال

عنوان ژورنال: Revista de filosofía DIÁNOIA

سال: 1978

ISSN: 1870-4913,0185-2450

DOI: 10.22201/iifs.18704913e.1978.24.912